1st UK National HOPE in Liver Transplantation Masterclass

Thackray Museum, Leeds
12th June 2024

In collaboration with

Introduction to Organ Preservation

Introduction to the Masterclass

Barbara Fiore, St James’s University Hospital, Leeds

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Introduction to Organ Preservation

Joerg-Matthias Pollok, Royal Free Hospital, London

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Physiology of Organ Machine Perfusion

Carlo Ceresa, Royal Free Hospital, London

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Techniques and Modalities of Organ Machine Perfusion

Rodrigo Figueiredo, The Freeman Hospital, Newcastle (30 min.)

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Overview of Current Clinical Evidence for HOPE

Sam Tingle, The Freeman Hospital, Newcastle

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Implementing HOPE in the United Kingdom – What? When? How?

Moderator: Joerg-Matthias Pollok

Contributors: Rodrigo Figueiredo, Barbara Fiore and Carlo Ceresa

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Practical Applications and Innovations in Organ Machine Perfusion

Assessment of liver graft quality during HOPE

Philipp Dutkowski, Basel

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UK Viability Sampling – a National standard?

Emily Thompson, Newcastle

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HOPE Viability Round Table

Moderator: Joerg-Matthias Pollok

Contributors: Emily Thompson and Philipp Dutkowski

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Practical Implementation of a HOPE programme and Closing Remarks

Keziah Crick, Royal Free Hospital, London

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Speakers

Barbara Fiore

Leeds

Bio

Rod Figueiredo

Newcastle

Bio

Samuel James Tingle, MD (PhD Candidate)

Newcastle University in Newcastle upon Tyne, England, School of Biomedical Sciences

Dr. Tingle is a surgeon and PhD candidate at Newcastle University. He is a Specialist Registrar in Surgery and an MRC Clinical Research Fellow in Transplantation. Dr. Tingle has maintained a relationship with the transplantation team at the Freeman Hospital since medical school, facilitating his continual involvement in multiple laboratory-based, translational and clinical research projects throughout his MRes, Academic Foundation Programme and Academic Clinical Fellowship. His research interests include machine perfusion, registry analysis, big data and meta-analysis.

Dr. Tingle is currently a Medical Research Council Clinical Research Fellow and Cochrane Clinical Answers Associate Editor. He is a member of the Royal College of Surgeons. Dr. Tingle is the recipient of the North East Surgical Training Academy NESTAC Medal for oral presentation of research, and is the recipient of several research grants, including most recently MRC Clinical Research Training Fellowship, with joint Kidney Research UK funding, the Wellcome Trust Translational Partnership – Early Translational Funding and Quality in Organ Donation Research Grant.

Dr. Tingle’s first-author publications include Donor Liver Blood Tests and Liver Transplant Outcomes: UK Registry Cohort Study, Transplantation, and Machine perfusion in liver transplantation. Cochrane Database of Systematic Reviews.

Philipp Dutkowski Prof. Dr. Med.

Professor of Surgery, Deputy Head of Visceral Surgery

University Hospital Basel, Switzerland

Philipp Dutkowski, MD is currently Professor of Surgery at the University Hospital Basel, Switzerland where he recently joined to start their liver transplant program. Prior to this appointment, he was Head of Abdominal Organ Transplantation and Director of the Liver Transplant Program in Zurich. He started his surgical career in 1993 in Germany at the University of Mainz, and completed his board certification for Surgery in 1999, and for Visceral Surgery in 2002. In parallel, he completed his thesis for Habilitation in 2001, after establishing a research group in the field of liver preservation. In 2004, he joined the group of Pierre Alain Clavien in Zurich, and succeeded to translate basic research on machine liver perfusion into clinical application. Since 2009, he leads the abdominal transplant program in Zurich.

David Nasralla

Royal Free

Bio

Keziah Crick

Royal Free

Bio

Colin Wilson

Newcastle

Bio